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Setting up the TRB program

Specific ramp rates are required for different thermocyclers for the Target RNA barcoding (TRB) program

Video tutorial:

Thermocycler Supplier/Vendor Ramp Rate Total Time*  Time to 95°C 
MiniAmp Thermo Fisher 3.5°C/s 8 mins 12 s 85 s
Mastercycler® X50 Eppendorf 1°C/s 6 mins 33 s 92 s
C1000 Touch Thermal Cycler Biorad 1°C/s 7 mins 53 s 96 s

*The total time listed is the actual run time of the program after the 4°C hold step, and not the estimated duration provided by the thermocyclers.

 

We recommend doing a test run before running the assay to ensure that the program runs as expected.

If your thermocycler is not listed above, time the program to achieve a total time of 6.5 mins to 8.5 mins and time to 95°C of 80 s to 100 s.